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Barbara Belletti Selected Research

Stathmin

5/2022HMGA1 positively regulates the microtubule-destabilizing protein stathmin promoting motility in TNBC cells and decreasing tumour sensitivity to paclitaxel.
1/2019Stathmin Is Required for Normal Mouse Mammary Gland Development and Δ16HER2-Driven Tumorigenesis.
10/2016p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms.
1/2014Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.
5/2013Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.
1/2012Stathmin is dispensable for tumor onset in mice.
11/2011Stathmin: a protein with many tasks. New biomarker and potential target in cancer.
5/2008Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.
1/2005p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.

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Barbara Belletti Research Topics

Disease

30Neoplasms (Cancer)
01/2022 - 01/2004
18Breast Neoplasms (Breast Cancer)
05/2022 - 04/2003
6Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 05/2013
5Neoplasm Metastasis (Metastasis)
05/2022 - 05/2008
5Ovarian Epithelial Carcinoma
01/2020 - 06/2013
4Carcinogenesis
01/2019 - 01/2012
4Carcinoma (Carcinomatosis)
01/2019 - 04/2003
3Disease Progression
01/2021 - 12/2019
3Inflammation (Inflammations)
01/2016 - 01/2004
2Squamous Cell Carcinoma of Head and Neck
01/2021 - 07/2017
2Wounds and Injuries (Trauma)
08/2014 - 05/2014
2Surgical Wound
05/2014 - 03/2008
2Sarcoma (Soft Tissue Sarcoma)
05/2008 - 01/2005
1Triple Negative Breast Neoplasms
05/2022
1Colorectal Neoplasms (Colorectal Cancer)
10/2021
1Noninfiltrating Intraductal Carcinoma (DCIS)
01/2020
1Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2018
1Prostatic Neoplasms (Prostate Cancer)
01/2018
1Genomic Instability
01/2017
1Pituitary Neoplasms (Pituitary Adenoma)
01/2014
1Papilloma (Papillomatosis)
01/2012
1Glioblastoma (Glioblastoma Multiforme)
05/2008
1Colonic Neoplasms (Colon Cancer)
01/2004
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2004
1Adenoma (Adenomas)
10/2003
1Goiter
10/2003

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
05/2022 - 04/2003
9StathminIBA
05/2022 - 01/2005
8Biomarkers (Surrogate Marker)IBA
01/2022 - 11/2011
7PlatinumIBA
01/2021 - 01/2017
4Hormones (Hormone)IBA
01/2022 - 01/2018
4Phenobarbital (Luminal)FDA Link
01/2021 - 01/2017
4Phosphotransferases (Kinase)IBA
10/2020 - 12/2013
4Biological ProductsIBA
12/2019 - 03/2008
3Messenger RNA (mRNA)IBA
01/2021 - 04/2003
3MicroRNAs (MicroRNA)IBA
01/2020 - 06/2013
2Cyclin DIBA
01/2022 - 10/2021
2Cyclin-Dependent Kinases (cdk Proteins)IBA
06/2021 - 05/2010
2Estrogen ReceptorsIBA
06/2021 - 01/2020
2Ribosomal Proteins (Ribosomal Protein)IBA
01/2016 - 05/2014
270-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
01/2016 - 05/2014
2CarcinogensIBA
01/2012 - 03/2007
2CyclinsIBA
03/2011 - 05/2010
1ChromatinIBA
05/2022
1palbociclibIBA
10/2021
1Cisplatin (Platino)FDA LinkGeneric
01/2021
1Cell-Free Nucleic AcidsIBA
01/2021
1Sp1 Transcription FactorIBA
01/2021
1Monoclonal AntibodiesIBA
01/2021
1Cetuximab (Erbitux)FDA Link
01/2021
1GlucocorticoidsIBA
10/2020
1Glutamine (L-Glutamine)FDA Link
01/2020
1human ERBB2 proteinIBA
01/2020
1RNA Splicing FactorsIBA
01/2020
1PTB-Associated Splicing FactorIBA
01/2020
1Epidermal Growth Factor (EGF)IBA
01/2020
1LigandsIBA
01/2020
1Proline (L-Proline)FDA Link
01/2020
1Glu Transfer RNAIBA
12/2019
1ErbB Receptors (EGF Receptor)IBA
12/2019
1NucleolinIBA
12/2019
1Ubiquitin-Specific ProteasesIBA
01/2019
1Cyclin-Dependent Kinase Inhibitor p27IBA
01/2018
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2016
1dacomitinibIBA
10/2016
1Protein Isoforms (Isoforms)IBA
10/2016
1Lapatinib (GW572016)FDA Link
10/2016
1saracatinibIBA
10/2016
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
10/2016
1STAT Transcription FactorsIBA
08/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2014
1CytokinesIBA
08/2014
1Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
08/2014
1sanguinarineIBA
08/2014
1Apoptosis Regulatory ProteinsIBA
05/2014
1Indicators and Reagents (Reagents)IBA
05/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013
13-methylcholanthryleneIBA
01/2012
1NitrosaminesIBA
01/2012
1Tumor Viral Antigens (Large T Antigen)IBA
01/2012
1Acetates (Acetic Acid Esters)FDA Link
01/2012
1DNA (Deoxyribonucleic Acid)IBA
10/2005
1Oxygen (Dioxygen)IBA
01/2004
1Oxidants (Oxidizing Agents)IBA
01/2004
1DemulcentsIBA
01/2004
1AntioxidantsIBA
01/2004
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2004
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
01/2004
1Cyclin D3IBA
10/2003
1BRCA1 ProteinIBA
04/2003

Therapy/Procedure

15Therapeutics
01/2021 - 05/2008
6Drug Therapy (Chemotherapy)
01/2021 - 06/2013
2Radiotherapy
01/2021 - 03/2008
1Oral Administration
08/2014
1Segmental Mastectomy (Lumpectomy)
03/2008